Home Science Brain Pathway Links Inflammation to Loss of Motivation in Advanced Cancer

Brain Pathway Links Inflammation to Loss of Motivation in Advanced Cancer

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Researchers at WashU Medicine identified a direct connection between cancer-related inflammation and the loss of motivation characteristic of advanced cancer. In a mouse study they describe a brain pathway that starts with neurons (labeled in green, above) that sense inflammation signals, and the researchers were able to treat the loss of motivation by blocking this pathway.

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