Home Science Post-trauma drug blocks fear response in female mice

Post-trauma drug blocks fear response in female mice

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hachi
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Nk3R antagonism decreases fear memory consolidation. (A) Experimental procedure of fear memory consolidation after stress. Created with Biorender. (B) Fear acquisition and expression in mice administered with Osanetant. (C) Effect in the fear memory consolidation after administration of Osanetant (5 mg/kg, ip) or Vehicle 30 min after stress (IMO) in adult females (n = 12 per group) (p = 0.038, η2 = 0.798). Analyzed by Generalized Linear Model with least significant difference (LSD) correction.

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